THE DEVELOPMENT, IMPLEMENTATION AND EVALUATION OF CLINICAL PATHWAYS FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) IN SASKATCHEWAN: PROTOCOL FOR AN INTERRUPTED TIMES SERIES EVALUATION

Abstract Background Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs; it is expected to be the third leading cause of death worldwide by 2030.To minimize these costs high quality guidelines have been developed.However, guidelines alone rarely result in meaningful change.One method of integrating guidelines into

Research background: The global SARS-CoV-2 pandemic is unprecedented for human society.Despite the continuing uncertainty about the future, it is certain that the global consequences of the pandemic will have many dimensions.Among others, the economic impacts are extremely significant.However, the sudden slowdown in economic activity, the declared

Histone methyltransferases are epigenetic regulators that modify key lysine and arginine residues on histones and are believed to play an important role in cancer development and maintenance.These epigenetic modifications are potentially reversible Volumizer and as a result this class of enzymes has drawn great interest as potential therapeutic tar

This work evaluated the potential of the acidification equalization tank (AET) used as a primary treatment unit, treating the hog farming wastewater.The treatment system consisted of a degritter with a triangular-notch weir, for measuring the flow, a static sieve, and an acidification and equalization tank (AET), an anaerobic baffled reactor (ABR),